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Post-doctoral position in Microbiology

ABG-100477 Emploi Confirmé
08/10/2021 CDD 12 Mois Salaire à négocier
University of Fribourg, Switzerland
Fribourg - Suisse
Santé, médecine humaine, vétérinaire
15/11/2021
Post-doctoral position in Microbiology

Employeur

Emerging antibiotic resistance is being recognized as a crosscutting threat to global health. Multidrug resistance is observed currently mostly in Gram-negative bacteria. It is dominated by the emergence of carbapenemase producers and to a certain extend to resistance to polymyxins and fosfomycin. Carbapenemases are bacterial β-lactamases that hydrolyze almost all broad-spectrum β-lactams, including the carbapenems (i.e. imipenem). Curtailing their spread requires a better understanding of the plasticity of carbapenemase genes at different levels, from bacterial species constituting their reservoir to their final host, once acquired. Polymyxins and Fosfomycin are now considered as last resort antibiotics for treating infections due to multidrug resistant bacterial infections

Poste et missions

To work in a  clinically-relevant projects at the interface of genetics, biochemistry and medical microbiology.

 

Your project:  You will investigate in particular the mobilization processes of resistance genes from their natural reservoirs to their targets and participate to decipher any novel  antibiotic resistance mechanisms including to fosfomycin. You will also contribute to the discovery of novel resistance genes that are spreading worldwide,  to develop novel rapid diagnostic tests for antibiotic resistance detection and evaluate/develop novel antibiotics .

 

We offer:  Cutting-edge research projects, excellent research facilities and  full funding and  the possibility to join a ver highly competitive group ((https://www.ncbi.nlm.nih.gov/pubmed/?term=nordmann+p

Mobilité géographique :

Internationale

Prise de fonction :

01/01/2022

Profil

You have: a PhD degree in Life Sciences or/and MD/Pharm D degree in  Medicine/Pharmacy  and a strong interest in studying antibiotic resistance in the context of  molecular microbiology/and protein analyses. Knowledge in antimicrobial resistance and sequencing and genome analysis will be highly appreciated.

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