Internship - Synthetic biology for protein production

Biomemory is dedicated to minimizing the data storage industry's carbon footprint through innovative biology. We aim to develop an economical and environmentally friendly DNA data storage solution, addressing the critical challenge of accommodating rapidly expanding data volumes while significantly cutting ecological impacts.

The company is located in Paris. The storage solution we envision building is based on new kind of DNA synthesis developed by Biomemory and its academic partners: CNRS and Sorbonne Université.

We're looking for an enthusiastic, driven, and talented student in biochemistry or molecular biology to bring their passion and expertise to our innovative, multidisciplinary team.

Find more informations here: https://www.biomemory.com/jobs

Internship opportunity in Biochemistry

Synthetic biology for protein production

Paris, Île-de-France, France

6-month full-time internship (final-year engineering or Master’s 2 student) - Starting early 2024

Application deadline: October 18th, 2024

Description

Biomemory is dedicated to minimizing the data storage industry's carbon footprint through innovative biology. We aim to develop an economical and environmentally friendly DNA data storage solution, addressing the critical challenge of accommodating rapidly expanding data volumes while significantly cutting ecological impacts.

The company is located in Paris. The storage solution we envision building is based on new kind of DNA synthesis developed by Biomemory and its academic partners: CNRS and Sorbonne Université.

We're looking for an enthusiastic, driven, and talented student in biochemistry or molecular biology to bring their passion and expertise to our innovative, multidisciplinary team.

Find more informations here: https://www.biomemory.com/jobs

Your Missions

By joining the Biochemistry team at Biomemory, you will play a pivotal role in the company’s R&D projects. You will contribute to developing and optimizing microbial expression platforms through synthetic biology with a focus on expression systems for the production, purification, and enzymatic testing of recombinant proteins. Your missions will include:

• Engineering bacterial strains through chromosomal manipulation
• Cloning and screening de novo protein expression technologies
• Developing and optimizing protein production using novel approaches
• Optimizing scale-up production processes
• Producing and purifying target proteins
• Performing functional characterization and analysis of target proteins

Requirements

This internship is for you if:

• You are in the final year of an engineering program or enrolled in a Master’s 2 program in biochemistry, molecular biology, biotechnology, life chemistry, or bioprocess engineering
• You have theoretical and practical knowledge of molecular biology techniques (nucleic acid manipulation, PCR, molecular cloning)
• You have theoretical and practical expertise in microbial genetic editing (knockout and knock-in via bacterial chromosomal recombination)
• You are skilled in the theoretical and practical aspects of protein purification (culturing, induction, liquid-phase chromatography)
• You possess a theoretical understanding of enzymology
• You have proficiency in reading and writing technical and scientific documents
• You have an English proficiency level ranging from B2 to C1 (Common European Framework of Reference for Languages)
• You are proficient with Microsoft Office, Google Docs, and sequence analysis software

What would be a plus ?

• Proficiency in the use of a bioreactor
• Knowledge or expertise in automation in biology, for example piloting pipetting robots
• Knowledge of 3rd generation sequencing techniques, for example Oxford Nanopore

Soft skills

The applicant should have a collaborative mindset and enjoy working in a multidisciplinary team:

• Team work, team spirit

• Ability to work effectively independently

• Demonstrated proactivity

• Organizational skills

• Critical thinking, technical rigor

• Openness to bi-directional feedback

• Solution oriented

• Intellectual and personal rigor, honesty and integrity

Recruitment process

• An initial 30-60 minute video interview with the direct supervisor
• A 60-minute on-site interview, featuring a case study assessment
• An on-site informal meeting with the co-founders and the team

All candidates are encouraged to provide 1 to 3 references and to submit their academic records.

Requirements

This internship is for you if:

• You are in the final year of an engineering program or enrolled in a Master’s 2 program in biochemistry, molecular biology, biotechnology, life chemistry, or bioprocess engineering
• You have theoretical and practical knowledge of molecular biology techniques (nucleic acid manipulation, PCR, molecular cloning)
• You have theoretical and practical expertise in microbial genetic editing (knockout and knock-in via bacterial chromosomal recombination)
• You are skilled in the theoretical and practical aspects of protein purification (culturing, induction, liquid-phase chromatography)
• You possess a theoretical understanding of enzymology
• You have proficiency in reading and writing technical and scientific documents
• You have an English proficiency level ranging from B2 to C1 (Common European Framework of Reference for Languages)
• You are proficient with Microsoft Office, Google Docs, and sequence analysis software

What would be a plus ?

• Proficiency in the use of a bioreactor
• Knowledge or expertise in automation in biology, for example piloting pipetting robots
• Knowledge of 3rd generation sequencing techniques, for example Oxford Nanopore

Soft skills

The applicant should have a collaborative mindset and enjoy working in a multidisciplinary team:

• Team work, team spirit

• Ability to work effectively independently

• Demonstrated proactivity

• Organizational skills

• Critical thinking, technical rigor

• Openness to bi-directional feedback

• Solution oriented

• Intellectual and personal rigor, honesty and integrity