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Postgraduate Position in Machine Learning for Cell-Free Systems

ABG-84626 Emploi Niveau d'expérience indifférent
19/04/2019 CDD 12 Mois Salaire à négocier
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INRA
Jouy-en-Josas - Ile-de-France - France
Biologie
  • Biotechnologie
  • Informatique
bioinformatique, apprentissage
Recherche et Développement

Employeur

MICALIS (INRA & AgroParisTech, Jouy-en-Josas) is a research unit of more than 350 researchers developing multidisciplinary approaches and promoting microbial systems biology towards the development of synthetic biology applications for health and biotechnology. Within MICALIS, the recruiting research team specializes in developing whole-cell and cell-free synthetic biology for pathway and biosensor engineering to produce biologically active molecules and monitor disease biomarkers.

Poste et missions

The person recruited is expected to develop: (i) state-of-the-art supervised machine learning tools to predict activities of engineered metabolic pathways, and (ii) a reinforcement/active learning pipeline to propose novel pathway sequences for synthesis and experimental characterization. These tasks will be performed using training sets built from experimental data already obtained by the host laboratory. The person recruited will also benefit from several years of experience the research team has in developing machine learning for systems & synthetic biology.

The position will necessitate interactions with molecular biologists. The persons recruited will closely collaborate with a IT research engineer, a postdoctoral appointee working on synthetic biology workflow developments, and wet laboratory research scientists already accustom to work together.

Mobilité géographique :

Pas de déplacement

Prise de fonction :

01/07/2019

Profil

  • Applicants should have a master, an engineering, or a Ph.D. degree in either: systems & synthetic biology, molecular biology, computational biology, or computer science with working knowledge of biology.
  • Ability to write high-quality research manuscripts, strong collaborative skills, and excellent communication skills in English are required.
  • Experience with machine learning open source tools is anticipated

Objectifs

By the end of the 1-year contract sufficient data should have been acquired using the active learning pipeline to write a high profile journal manuscript.

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