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Post-doctoral position in lymphoma research

ABG-86634 Emploi Confirmé
11/07/2019 CDD 12 Mois > 45 et < 55 K€ brut annuel
Inserm UMR 1231
Dijon - Bourgogne-Franche-Comté - France
Biologie
  • Biochimie
Lymphoma, epigenetics, pre-clinical models
Recherche et Développement

Employeur

1-year fixed-term contract with high probability for at least one more year, full time.

 

Start date: from October 2019 to January 2020

 

We are seeking to recruit an outstanding and highly motivated postdoctoral researcher to join the Signaling and Physiology in Hematological Research (SAPHIHR) Laboratory, led by Prof. Mary Callanan and Dr Laurent Delva at the Inserm Research Center in Dijon. Our lab focuses on understanding the (epi)genetic mechanisms that drive the initiation and progression of lymphoma and leukemia. Strong emphasis is on translation of findings to the clinic through pre-clinical research in cell line/mouse models and investigations in primary patient samples.

 

Further opportunities for scientific exchange are available within our Inserm center which hostsover 300 scientists in the fields of cancer / leukemia biology, immunology, genetics, metabolism and epidemiology.

Site web :

Poste et missions

The post-doctoral project is investigating a newly-identified mechanism of pathological heterochromatin reprogramming in B cell lymphoma and how this shapes disease evolution and anti-tumor immune responses. Special interest is on identification and therapeutic targeting of novel functional vulnerabilities related to altered heterochromatin homeostasis in these disorders.

You will work on your own research project and will be responsible for independently running experiments and day-to-day project management and development. The project will involve a high degree of teamwork, interdisciplinary research and flexibility in developing and managing complex and demanding experimental protocols and data sets.

Mobilité géographique :

Pas de déplacement

Prise de fonction :

01/11/2019

Profil

- A recent PhD in epigenetics, hematology, stem cell biology or related research field

- Experience with chromatin immunoprecipitation, biochemistry, in vivomodels, flow cytometry and gene expression methods

- Knowledge on hematopoiesis and data/statistical analysis associated with these fields

- Experience in bioinformatics would be an asset (bioinformatics support is available in the team)

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