Research Engineer in organic/medicinal chemistry

The LIT (http://medchem.unistra.fr) is a mixed laboratory between the University of Strasbourg and the Centre National de la Recherche Scientifique (CNRS). It has a long-standing experience in medicinal chemistry/chemical biology as well as an extensive record of accomplishment for developing preclinical candidates.

Within a European project framework (EJPRD/ERDERA), the candidate will synthesize analogues of a lead compound to develop a preclinical candidate for the treatment of a rare disease (Diamond-Blackfan anemia)

The candidate should have a PhD or Engineer diploma in organic chemistry with a strong experience in multi-step heterocyclic organic synthesis.

A preliminary experience in medicinal chemistry will be an asset.He (she) must be self-motivated, hard-working, independent thinker and have good communication skills and a good team spirit.

Within a 18-month period, the candidate should optimize an existing hit with respect to potency and ADMET properties and propose atttactive candidates for regulatory preclinical investigations.