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PhD in biophysics (M/F) – Biophysics ans biomechanics of plants exposed to nanoparticles of interest for agriculture

ABG-138694 Thesis topic
2026-04-23 Public funding alone (i.e. government, region, European, international organization research grant)
Nantes Université
NANTES - Pays de la Loire - France
PhD in biophysics (M/F) – Biophysics ans biomechanics of plants exposed to nanoparticles of interest for agriculture
  • Physics

Topic description

Understanding the mechanisms by which nanoparticles (NPs) interact with plants is crucial for, firstly, better identifying their impact on plant growth, their toxicity, their potential transmission through the food chain, and secondly, evaluating their potential use as nano-fertilizers. The main objective is to study the impact of NPs on cell biomechanics and plant cell wall properties, depending on the exposure dose. The particles will be chosen based on their relevance to agriculture. Two model plants will be used: Arabidopsis thaliana, a flowering plant of the Eudicots class, which includes many cultivated plants (rapeseed, cabbage, peas, cucumber, etc.), and Brachypodium distachyon, a herbaceous plant of the Monocots class related to cultivated grasses (barley, wheat, etc.)

This thesis aims to characterize the interactions between nano-fertilizers and plants. Understanding these interactions is crucial for the development of sustainable agriculture and for assessing the potential impact on human health. Indeed, the use of nano-fertilizers has been identified as an alternative to conventional fertilizers, as they should optimize nutrient supply, limit losses to the environment, and preserve crop production and quality.

Starting date

2026-10-01

Funding category

Public funding alone (i.e. government, region, European, international organization research grant)

Funding further details

Presentation of host institution and host laboratory

Nantes Université

The thesis work will include a significant experimental component, focused on the use of several characterization techniques, notably nanoindentation by atomic force microscopy, which allows the measurement of the elastic modulus of the plant cell wall perpendicular to the indentation and the quantification of hydrostatic pressure within the cell, and Raman spectroscopy, which provides information on the chemical composition, polymer organization, and distribution within the plant cell wall. A study of the differential expression of genes involved in cell wall metabolism will be also conducted.

The thesis will benefit from all the necessary resources provided by the laboratory for conducting the project, including access to the PLASSMAT characterization platform at the IMN. It will be developed in collaboration with the PVPP (Plant Cell Wall and Cell Wall Polymers) team of the BIA unit at INRAe ​​(Nantes).

Institution awarding doctoral degree

Nantes Université

Candidate's profile

The candidate will hold a Master's degree in nanoscience, physics, life sciences, or biophysics and will have a strong interest in interdisciplinarity.

2026-05-22
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