Structural Basis of Substrate Recognition by the Glycosaminoglycan Biosynthesis Machinery
| ABG-140196 | Sujet de Thèse | |
| 09/09/2026 | Financement public/privé |
- Biochimie
Description du sujet
A fully funded 3-year PhD position is available in the WILD team at the
Institut de Biologie Structurale (IBS) in Grenoble, France. The successful
candidate will contribute to a better understanding of the molecular
mechanisms underlying glycosaminoglycan biosynthesis. Our research
combines in vitro enzymatic assays with state-of-the-art biophysical
techniques, including nuclear magnetic resonance spectroscopy and
single-particle cryo-electron microscopy, to investigate substrate specificity and protein–protein interactions of key biosynthetic enzymes.
Nature du financement
Précisions sur le financement
Présentation établissement et labo d'accueil
You will join a young, dynamic, and international research team
working in an interdisciplinary environment. The Institut de Biologie
Structurale is located on the EPN campus in Grenoble and provides
excellent infrastructure for pursuing challenging structural biology
projects, as well as access to a vibrant scientific community.
Intitulé du doctorat
Pays d'obtention du doctorat
Etablissement délivrant le doctorat
Ecole doctorale
Profil du candidat
We are looking for a highly motivated and team-oriented candidate with:
- A Master’s degree in structural biology, protein biochemistry, or a related field.
- Strong practical experience in protein purification and characterisation.
- Previous experience in protein structure determination would be an advantage.
- Excellent written and oral communication skills in English.
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