Multiscale Study of Silicone Breast Implant Gel bleeding and Aging Mechanisms

ERRMECe unit studies the interrelationships between cells and their various environments (natural environments such as extracellular matrices, biofilms, microenvironments, materials, etc., or artificial environments such as surfaces, synthetic materials, biomaterials, etc.). These approaches are examined from molecular, supramolecular and cellular perspectives. ERRMECe brings together biochemists, cell biologists, physiologists, microbiologists and physical chemists, combining these different areas of expertise at both a fundamental and applied level in the study of cell/environment interactions in the context of pathology, the development of innovative materials and biomaterials, industrial processes and heritage preservation.

The recruited Master 2 student or Engineer will participate in an interdisciplinary research project dedicated to the physicochemical analysis of gel bleeding and aging in medical grade silicone breast implants. The objective is to characterize/evaluate the diffusion of low-molecular-weight Cyclic and Linear Siloxanes, understand the mechanisms of diffusion and degradation, and assess their impact on the biocompatibility and long-term performance of this medical device. This position is open to candidates with a background in biotechnology, chemistry, materials science, polymer science, or biomedical engineering, with strong motivation for experimental research at the interface between materials and health sciences.

This position is open to candidates with a background in biotechnology, chemistry, materials science,

polymer science, or biomedical engineering, with strong motivation for experimental research at the

interface between materials and health sciences.

Key competencies

Knowledge

o Solid background in polymer or materials chemistry, biomaterials, or biotechnology.

o Theoretical and practical knowledge of diffusion, transport, and degradation process in polymer systems.

o Familiarity with analytical techniques (FTIR, GC-MS, GC-FID, thermal analysis, UV spectroscopy).

o English language level: B2 or higher (CEFR).

Know-how

o Experience in polymer sample preparation and chemical analysis.

o Ability to manage multiple experiments simultaneously and ensure data traceability.

o Knowledge of laboratory safety procedures and good laboratory practices (GLP).

o Capacity to analyze and interpret spectroscopic and physicochemical data.

o Ability to synthesize and communicate results clearly in written and oral form, for both scientific

and industrial audiences.

Skills

• Strong interest in interdisciplinary work at the interface of materials science, chemistry, and biology.

• Rigor, organization, and autonomy in experimental work.

• Excellent communication and teamwork abilities.

• Curiosity, adaptability, and scientific creativity.